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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
10.61
Human Site:
T421
Identified Species:
21.21
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
T421
S
V
D
V
Q
R
L
T
E
S
V
L
Y
L
N
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
A286
D
E
N
N
I
L
D
A
Q
T
A
F
V
S
L
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
T386
M
R
L
R
S
A
I
T
G
L
V
Y
R
K
V
Dog
Lupus familis
XP_547113
1504
165780
T421
S
V
D
V
Q
R
L
T
E
C
I
I
Y
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
Y424
R
L
A
E
S
I
I
Y
L
N
G
L
W
L
L
Rat
Rattus norvegicus
O88269
1502
164977
H424
R
L
V
E
S
I
L
H
L
N
G
L
W
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
M447
S
V
D
A
Q
R
F
M
D
L
A
T
Y
I
N
Chicken
Gallus gallus
Q5F364
1525
170953
M434
S
V
D
A
Q
R
F
M
D
L
A
T
Y
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
M434
S
V
D
A
Q
R
F
M
D
L
I
T
Y
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
V329
F
L
S
L
V
G
Y
V
I
L
G
K
V
F
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
S434
A
V
D
A
Q
Q
L
S
D
M
M
L
Q
L
H
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
Q417
S
V
D
V
Q
K
L
Q
D
L
T
Q
W
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
80
N.A.
13.3
20
N.A.
46.6
46.6
N.A.
46.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
93.3
N.A.
40
40
N.A.
60
60
N.A.
66.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
34
0
9
0
9
0
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
0
59
0
0
0
9
0
42
0
0
0
0
0
0
% D
% Glu:
0
9
0
17
0
0
0
0
17
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
25
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
25
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
9
17
17
0
9
0
17
9
0
25
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
0
% K
% Leu:
0
25
9
9
0
9
42
0
17
50
0
34
0
50
25
% L
% Met:
9
0
0
0
0
0
0
25
0
9
9
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
0
17
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
59
9
0
9
9
0
0
9
9
0
0
% Q
% Arg:
17
9
0
9
0
42
0
0
0
0
0
0
9
0
0
% R
% Ser:
50
0
9
0
25
0
0
9
0
9
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
25
0
9
9
25
0
0
9
% T
% Val:
0
59
9
25
9
0
0
9
0
0
17
0
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% W
% Tyr:
0
0
0
0
0
0
9
9
0
0
0
9
42
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _